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Tolerance to lots of the outcomes of codeine, such as its therapeutic results, develops with prolonged use. This happens at distinct charges for different results, with tolerance to the constipation-inducing outcomes developing significantly slowly As an illustration.Get health care assistance immediately for those who discover any of the following

Having said that, critical withdrawal side effects can ordinarily be prevented by step by step decreasing the dose about a period of time before therapy is stopped fully. This medication is on the market only below a limited distribution software known as the Opioid Analgesic REMS (Risk Analysis and Mitigation Method) program. This solution is avai